Biomedical Engineering Reference
In-Depth Information
TABLE 5.1 Preparation of Methyl-3,4-dihydro-2
H
-pyran-5-carboxylates 3/4
Entry
Aldehyde
Enol Ether
Product
Yield (%)
a
3
:
4
b
1
3a/4a
,13 3.5:1
2
3b/4b
,13 1:1
3
3c/4c
,37 3.5:1
4
3d/4d
,21 4:1
5
3e/4e
,22 5:1
6
3f/4f
,32 5:1
7
3g/4g
,26 3.6:1
8
3h/4h
,20 3.3:1
9
3i/4i
,12 2.8:1
a
Isolated yields.
b
Ratios determined by NMR spectroscopy and GC analysis.
