Biomedical Engineering Reference
In-Depth Information
SCHEME 4.32
Values of GI
50
for modified GGTIs toward K562 cells (
M).
TABLE 4.12
IC
50
Values (
M) of Preferential RabGGTIs
RabGGTI
GGTase-I
RabGGTase
FTase
113a
>
50
4.5
>
100
113b
>
50
3.6
>
100
113c
>
50
4.8
>
100
113d
>
50
2.1
>
100
113e
>
50
2.2
>
100
SCHEME 4.33
Molecular structures and IC
50
values (
M) of preferential RabGGTIs.
