Biomedical Engineering Reference
In-Depth Information
modern omics technologies, the advanced characteristics of these strains were
elucidated in systematic levels. Chinese researchers also contributed to devel-
oping the currently most efficient gene knockout tool based on group II intron
in C. acetobutylicum, and some improvements in genetic manipulation on
C. acetobutylicum were achieved by Chinese researchers,viz., intron-anchored
targeted gene deletion, acceptance of unmethylated DNA, and electrotransfor-
mation in air. Some efforts are also being made to developing more efficient
genetic tools focusing on genome engineering. Currently, several engineered
strains have been reported by Chinese researchers, aiming to improve the strain's
fermentation performance. In addition, fermentation and separation technologies
have also been widely studied in China. Chinese researchers are also trying to
develop the ABE process using lignocellulosic feedstocks, for an sustainable and
economical process. We believe that more achievements in biobutanol produc-
tion will be published by Chinese researches in the future. Meanwhile, Chinese
researchers should pay more effort to contribute to the academic field with
creative ideas and fundamental research.
References
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