Biomedical Engineering Reference
In-Depth Information
Normal
Edematous
100 μm
1000 μm
100 μm
FWSHG
BWSHG
FWSHG
BWSHG
FIgurE 12.13 En face forward SHG (FWSHG) and backward SHG (BWSHG) images of untreated and edem-
atous bovine corneas at depths of 100 and 1000 mm. Note that in anterior part (100 mm), SHG images reveal
similar structures in both normal and edematous corneas. However, in the posterior region (1000 mm), a devia-
tion from the normal lamella orientation can be observed. (Adapted from Hsueh, C. M. et al. 2009. Biophys J
97(4):1198-1205.)
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