Biomedical Engineering Reference
In-Depth Information
Figure 42.6.
Detection of hydrogen peroxide with peroxalate nanoparti-
cles. (a) Sensitivity and (b)specificity.
fluorescentdyeshavegreatpotentialforimagingofhydrogenperox-
ide generated during inflammation-associated conditions.
Despite great promise for
in vivo
imaging of hydrogen perox-
ide using peroxalate polymer nanoparticles, their physicochemical
properties such as large size and hydrophobic surface nature limit
more biological applications. To overcome these limitations, per-
oxalate chemiluminescent micelles were developed. The micelles
exploited the same concept of three-component peroxalate
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