COLLAGEN-BASED SCAFFOLD FOR BONE TISSUE REGENERATION - Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine - page 773

lead to an improved understanding of collagen-mediated mineral-
ization in other calcified tissues and point the way to the develop-
ment of new functional materials for biomimetic engineering. This
knowledge will also help in the treatment of widespread patholog-
ical calcifications, such as atherosclerosis, stone formation, or den-
talcalculus.Furtherprogressinthetopicofcollagen-basedscaffolds
can be expected to come from modern genetics, where gene struc-
tures are now known to control the dynamic self-assembly of both
cellular and protein processes.
Acknowledgments
This work was supported by National Basic Research Program
of China, Grant No. 2005CB623905, and by the National Natural
Science Foundation of China, Grant No. 50830102.
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