Biomedical Engineering Reference
In-Depth Information
Figure 34.1.
Gross view (
top
, between arrows) and histology of engi-
neered tendon (
middle
) and natural tendon (
bottom
) at 14 weeks' postre-
pair. (Reprinted by permission from Ref. 11).
fibroblasts were used to replace tenocytes as seed cells to engi-
neer the tendon and repair tendon defects. As similarly described,
dermal fibroblasts were first isolated and
in vitro
-cultured and
expanded, and then the cells were seeded onto unwoven PGA
fibers for one week of
in vitro
culture. Scanning electron micro-
scope examination revealed abundant matrix production by both
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