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Figure 16.4.
Total sGAG production was normalized by the dried weight
ofeachsampleandrepresentedasrelativesGAGcontentinpercentage(%).
The sGAG production was higher in fibrin/PLGA seeded with AF cells (a)
and NP cells (b)than in the PLGA group.
culture.Themagnitudesweresignificantlyhigherby1.55-fold,1.33-
fold, and 1.2-fold after one week (
p
=
0.008), two weeks (
p
=
0.009), and three weeks (
p
=
0.038), respectively.
Approximately1
×
10
5
cellsperscaffoldwereculturedinthefib-
rin/PLGA and PLGA scaffolds. Seeded cells adhered onto the scaf-
folds, proliferated, and produced matrices filling in the void spaces
of the scaffolds. No sign of cartilaginous tissue formation in fib-
rin/PLGA and PLGA was observed after one week of
in vitro
3D
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