The Hammerhead Ribozyme: Structure, Catalysis, and Gene Regulation - Progress in Molecular Biology and Translational Science - page 16

Figure 1.4 Comparison of the CLEC2 hammerhead ribozyme sequences. Alignments of verified and predicted CLEC2 hammerhead ribozyme
sequences. The sequences of the substrate and enzyme segments were aligned using ClustalW2 ( http://www.ebi.ac.uk/Tools/clustalw2/index.
html ). The remainders of 3 0 UTRs are denoted as length of sequence in parentheses to the predicted stop codon and polyA signal. For reference,
the active site cytosine is indicated with an arrowhead, and other conserved catalytic core nucleotides are boxed. Residues predicted to form
base pairs in the double helices (including GU pairs) are highlighted in gray and correspond to stems indicated in the labels below the align-
ment. Asterisks mark nucleotides that are identical in all sequences.