Biomedical Engineering Reference
In-Depth Information
TABLE C.11: Cancer Cell Migration in Matrix Microchannels. () indicates
parameters that vary in the different sets of simulations.
Parameter
Description
Value
Reference
A
volume
;N
523 [m
3
]
Volume of cell nucleus
[28, 332]
A
surface
;N
314 [m
2
]
Surface of cell nucleus
[28, 332]
A
volume
;C
Volume of cell cytosol
6542 [m
3
]
[28, 332]
A
surface
;C
3140 [m
2
]
Surface of cell cytosol
[28, 332]
T
;N
Motility of cell nucleus
0.25
[357]
T
;C
Motility of cell cytosol
9
[357]
volume
;N;C
Cell compressibility
15
[357]
surface
;N
Stiffness of cell nucleus
15 ; 0.5*
[357]
surface
;C
Stiffness of cell cytosol
15 ; 0.9*
[357]
J
int
N;C
Generalized adhesion between nu-
cleus and cytosol
-20
[357]
J
ext
E;E
Cell{cell adhesive strength
12
[357]
J
ext
E;M
Cell{medium adhesive strength
0
[350]
J
ext
E;P
Cell{bronectin
gel
adhesive
0
[350]
strength
pers;0
Basal persistence strength
0.8
[357]
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