Biomedical Engineering Reference
In-Depth Information
Fig. 2 (a) Homogeneous/classical tumor growth gives rise to spherical shape. Heterogeneous
tumor growth after 50 (b), 200 (c), and 400 (d) time steps show asymmetric tumor shape with
irregular boundary. The proliferating, quiescent and necrotic layers are indicated as
bright
,
dark
,
and
light-dark
, respectively
Fig. 3 (a) The number of proliferating cells stabilizes as growth progresses. (b) The number of
cells of phenotypes II, III, and IV in tumor volume shows tumor heterogeneity
