Oxidative Stress and Species Differences in the Metabolism, Developmental Toxicity, and Carcinogenic Potential of Methanol and Ethanol - The Toxicology of Methanol - page 228

FIGURE 7.24 Effect of MeOH on embryopathies in mice overexpressing
human catalase. Double daggers indicate difference from saline treated
embryos of the same genotype ( 0.0001).

Asterisk and letter indicates difference between genotypes for the same
treatment group ( p

z p 0.05, zz p 0.01, zzz p

< < <

0.05; a, p ¼ 0.05). Source: From Miller and Wells

<

(2011).

with an increased incidence of ophthalmic abnormalities and cleft
palates; however, these incidences of anomalies were not significantly
different from those seen in hCat mice although there was a trend
for protection (Siu et al., 2013) (Figure 7.25). On the other hand,