Organic Electrode Reactions - Fundamentals and Applications of Organic Electrochemistry - page 138

(5.15)
5.3 Electrochemical Asymmetric
Synthesis
Asymmetric synthesis is a highly important
area in organic chemistry and a number of
asymmetric catalytic syntheses have recently
been developed. However, electrochemical
asymmetric synthesis is still immature
compared with well-established chemical,
catalytic and enzymatic methods. Various
methods for electrochemical asymmetric
synthesis have been proposed [33,34]: (i)
intramolecular asymmetric induction, (ii)
utilization of chiral solvents, (iii) use of chiral
supporting salts, (iv) use of chiral electrode
adsorbance, (v) use of electrodes chemically
modified with chiral substances, (vi) use of
chiral polymer-modified electrodes, (vii) use of
chiral mediators. Among these, (i) and (ii) are
not unique methodology characterized by
electrochemistry. However, a number of papers
dealing with these methodologies have been
reported. Although (iii) is a methodology
characterized by electrolysis, a large amount of
chiral supporting salt is required, therefore it is