Biomedical Engineering Reference
In-Depth Information
( A )
( B )
( C )
( D )
( E )
Figure 13.12 ( A ) A 55-year-old Thai woman with melasma, before treatment. ( B ) Erythema was noted 1 week after two-pass CO 2 laser resurfacing. ( C ) Postinfl am-
matory hyperpigmentation developed 4 weeks after treatment. ( D ) Again 4 weeks after treated with hydroquinone 4% cream twice daily, hyperpigmentation had
faded. ( E ) Pseudohypopigmentation without recurrence of melasma on the resurfaced area 4 years after treatment. She received no further topical bleaching agent
but used only an SPF 30, broad spectrum sunscreen.
Dermal Pigmented Lesions
Nevus of Ota
Nevus of Ota, a dendritic melanocytosis of the papillary and
upper reticular dermis involving the eye and surrounding skin
innervated by the fi rst and second branches of the trigeminal
nerve, is a cosmetic problem commonly found in Asians but is
also seen in blacks and whites. An incidence of 0.6% has been
noted in the Japanese (108). Malignant degeneration has occa-
sionally been reported (109,110). Studies in fair- and dark-
skinned populations have demonstrated that red (QS ruby)
(111-113), near infrared (QS alexandrite) (114-117), and QS
Nd:YAG (76,118) lasers are very useful for treating nevus of
Ota with fading over several months following each treatment
session.
 
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