ENGINEERING OF CELL-PENETRATING PEPTIDE-CONJUGATED INTRACELLULAR DELIVERY SYSTEMS - Biologically-Responsive Hybrid Biomaterials - page 223

Polyethylene glycol PEG

Enhanced permeability and retention EPR

Phosphatidylethanolamine PE

Polyethylenimine PEI

Thiocholesterol-based cationic lipids TCL

Nanolipoparticles NLPs

Antigen presenting cells APC

Multifunctional envelope-type nano device MEND

Poly- -lysine PLL

Dioleoylphosphatidylethanolamine DOPE

Cholesteryl hemisuccinate CHEMS

Drug delivery system DDS

para -nitrophenyl pNP

Adenosine-5'-triphosphate ATP

Transmission electron microscopy TEM

Solid lipid nanoparticles SLN

References

[1] Berry, C.C., “Intracellular delivery of nanoparticles via the HIV-1 tat peptide,” Nanomed ,
Vol. 3, No. 3, 2008, pp. 357-65.
[2] Torchilin, V.P., “Tatp-mediated intracellular delivery of pharmaceutical nanocarriers,”
Biochem Soc Trans , Vol. 35, No. Pt 4, 2007, pp. 816-20.
[3] Lindgren, M., et al., “Cell-penetrating peptides,” Trends Pharmacol Sci , Vol. 21, No. 3,
2000, pp. 99-103.
[4] Zorko, M., and Langel, U., “Cell-penetrating peptides: mechanism and kinetics of cargo
delivery,” Adv Drug Deliv Rev , Vol. 57, No. 4, 2005, pp. 529-45.
[5] Vives, E., Brodin, P., and Lebleu, B., “A truncated HIV-1 Tat protein basic domain rapidly
translocates through the plasma membrane and accumulates in the cell nucleus,” J Biol
Chem , Vol. 272, No. 25, 1997, pp. 16010-7.
[6] Derossi, D., et al., “The third helix of the Antennapedia homeodomain translocates through
biological membranes,” J Biol Chem , Vol. 269, No. 14, 1994, pp. 10444-50.
[7] Elmquist, A., et al., “VE-cadherin-derived cell-penetrating peptide, pVEC, with carrier
functions,” Exp Cell Res , Vol. 269, No. 2, 2001, pp. 237-44.
[8] Rojas, M., et al., “Genetic engineering of proteins with cell membrane permeability,” Nat
Biotechnol , Vol. 16, No. 4, 1998, pp. 370-5.
[9] Oehlke, J., et al., “Cellular uptake of an alpha-helical amphipathic model peptide with the
potential to deliver polar compounds into the cell interior non-endocytically,” Biochim
Biophys Acta , Vol. 1414, No. 1-2, 1998, pp. 127-39.
[10] Pooga, M., et al., “Cell penetration by transportan,” Faseb J , Vol. 12, No. 1, 1998, pp. 67-
77.