Biology Reference
In-Depth Information
Table 2.
(
Continued
)
Structural or
HSV-1
HCMV
KSHV
Location
Protein
Functional Roles
Tegument
UL24
UL76
ORF20
Fusion protein
protein
Tegument
UL23
Unknown
ORF21
Thymidine kinase
protein
Tegument
No
No
ORF45
IRF7-binding protein
protein
homologue
homologue
homologue
Tegument
No
No
ORF75c
Unknown
protein
homologue
homologue
Envelope glycoproteins
gB
UL27
UL55
ORF8
Major envelope
protein, binds cellular
integrin receptor
gH
UL22
UL75
ORF22
Second most abundant;
forms gH/gL/gO
gp150
No
No
M7
Binds heparin
homologue
homologue
sulfate; conserved among
gammaherpesviruses
MCP, major capsid protein; mCP, minor capsid protein; mC-BP, minor capsid binding protein; SCP, smallest capsid protein;
HMWP, high-molecular-weight protein; gB/gH/gL/gO, glycoproteins B/H/L/O; IRF, interferon regulatory factor.
