Biology Reference
In-Depth Information
Table 2.
Major Virion-associated Proteins of HSV-1, HCMV, and KSHV
Structural or
HSV-1
HCMV
KSHV
Location
Protein
Functional Roles
Capsid shell
MCP
UL19
UL86
ORF25
Forms pentons, hexons
mCP
UL18
UL85
ORF26
Triplex dimer protein
mC-BP
UL38
UL46
ORF62
Triplex monomer protein
SCP
UL35
UL48.5
ORF65
Binds the upper domains
of hexons
Portal
Portal protein
UL6
UL104
ORF43
Portal protein
Inside capsid
Protease
UL26
UL80
ORF17
Maturation protease
Scaffold
UL26.5
UL80.5
ORF17.5
Scaffolding protein
Tegument layer
Tegument
UL36
UL48
ORF64
HMWP, binds capsid
protein
Tegument
UL37
UL47
ORF63
Binds HMWP
protein
Tegument
UL25
UL77
ORF19
Binds capsid vertices
protein
Tegument
UL34
UL50
ORF67
Capsid-docking protein on
protein
nuclear lamina
(Continued)
