Biomedical Engineering Reference
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(b)
Figure 5. Continuation.
interfacial phenomena since neither insulating substrates nor elec-
trochemically-inactive substances limit SECM applications. As
introduced in the preceding section, current research on DNA ar-
rays suggests that the electronics arrays are best suited for electro-
chemical DNA analysis purposes. However, for their potential
high-throughput capabilities, electronics arrays require a multi-
plexer circuit element or hardware equipment to readout the mas-
sive signal in a single procedure. SECM imaging, with its high
spatial resolution, clearly has the potential to be an alternative
method, even if it is subjected to a spot-type DNA array with a
conventional design. During the last few decades, theoretical de-
scriptions of SECM have been built and include
(a) how the Faradaic current flow varies into/out of the tip ac-
cording to the tip-to-substrate distance, and
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