Biomedical Engineering Reference
In-Depth Information
Fig. 12.2
An illustration of 20 cases with/without IAs. The reconstructed section is depicted in
dark blue
whilst the IA is depicted in
light blue
Canonsburg, PA) and an unstructured tetrahedral mesh with prism layers lining
the boundary is generated for the fluid domain. Blood is modeled as an incom-
pressible Newtonian fluid with constant density
ρ
1069 kg m
−
3
=
and viscosity
η
0
.
0035 Pa s. At the arterial wall, no slip, no-flux conditions are applied. Pul-
satile flow and pressure boundary conditions for the inlets and outlets of the fluid
domain are taken from a 1D model of the arterial tree (Reymond et al.,
2009
) which
has been integrated into the software suite @neufuse. It solves the 1D form of the
Navier-Stokes equation in a distributed model of the human systemic arteries, ac-
counting for the ventricular-vascular interaction and wall viscoelasticity; it was re-
cently validated through a comparison with in vivo flow measurements (Reymond
et al.,
2011
). The incompressible Navier-Stokes equations which govern the flow
are solved with ANSYS CFX (ANSYS Inc., Canonsburg, PA) using a finite volume
formulation.
=
12.2.2 Results
CFD simulations are performed on 22 clinical cases with IAs removed. Spatial dis-
tributions of several hemodynamic indices are analyzed and compared with respect
