Biomedical Engineering Reference
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Fig. 9.17 Impedance in its complex representation and its equivalent Bode plot for the COPD di-
agnosed group. The stars denote estimated impedance using ( 3.8 ), while a continuous line denotes
the averaged values
To verify if the T index changes by COPD severity, the subdivision of the COPD
patients according to the GOLD classification is used. Although the number of pa-
tients is too low to provide a meaningful statistical difference, Fig. 9.26 shows a
clear difference in the amount of non-linear distortions with gradual severity of the
disease. This indeed delivers a proof of concept that non-linearity increases with
disease severity ( p
0 . 01).
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