Chemistry Reference
In-Depth Information
In practice, for organic synthesis, the limit is often when the substrate is consumed, even if the catalyst is
still active. Hence, for practical purposes, TON quoted will be calculated based upon the number of moles
of product formed divided by the number of moles of catalyst employed, so a reaction proceeding in 80%
chemical yield with 5 mol% of a catalyst will have a turnover number of 80
16.
39
TOF is the turnover
/
5
=
number per unit time.
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