MRI with Gadolinium-Based Nanoparticles - Nanotechnology for Biomedical Imaging and Diagnostics - page 228

Divergent approach:

PG

1. PG
PG
2. Deprotection

1. PG
PG
2. Deprotection

1.

PG
2. Deprotection

G0

G1

G2

G3

Convergent approach:

PG

Deprotection

PG

PG PG

G4

= Trifunctional core
= Protective group PG

FIGuRe 8.3 strategies for the synthesis of a G4 dendrimer via the divergent and the convergent approaches.