Hollow Nanocapsules in Biomedical Imaging Applications - Nanotechnology for Biomedical Imaging and Diagnostics - page 85

(c)

(a)

100 nm

(g)

12
10
8
6

A
B
C
D
E
F

100 nm

100 nm

4
2

(d)

(f)

1 10 100 1000

D (nm)

(e)

100 nm

100 nm

100 nm

Figure 4.5 DLS and TEm images of NCs prepared by varying monomer-to-lipid (m:L)
and monomer-to-cross-linker (m:C) ratios. In these experiments, liposomes loaded with
monomers were irradiated with uV light for 90 min and treated with Triton X-100. Initial ra-
tios used for the preparation of monomer-loaded liposomes were as follows: (a) m:L = 3:1,
m:C = 1:1; (b) m:L = 2:1, m:C = 1:1; (c) m:L = 1:1, m:C = 1:1; (d) m:L = 0.5:1, m:C = 1:1; (e)
m:L = 3:1, m:C = 10:1; (f) m:L = 3:1, no cross-linker; (g) DLS data of all NCs. (Reprinted and
adapted with permission from Ref. [17]. © American Chemical Society.)

(a) (b) (c)

Figure 4.6 Different polymer morphologies from vesicle templating. (a) Parachutes; (b)
necklaces; and (c) matrioshka structures. (Reprinted with permission from Ref. [12]. © Pergamon.)