Vibrational Spectroscopy and Cancer - Vibrational Spectroscopy for Tissue Analysis - page 74

Table 4.7
Articles on Gastrointestinal Tissue (Other than Colon)

Research
Group

Research
Method

Investigated Tissue or
Sample

Effectiveness of
the Technique

Reference
Number

Barr et al. Review n/a n/a 42

Petrich Review n/a n/a 43

Fujioka et al. FTIR Gastrointestinal tissue + 99

Tan et al. Raman Gastrointestinal tissue + 100

Weng et al. Raman and

FTIR

Gastrointestinal tissue + 101

Mordechai et al. FTIR Intestine + 102

Shetty et al. Raman Oesophageal tissue + 103

Li et al. FTIR Gastric tissue + 104

Xu et al. FTIR-ATR Stomach tissue + 105

Suzuki et al. Raman Pancreatic tumour tissue + 106

Kawabata et al. Raman Gastric tissue + 107

Teh et al. Raman Gastric tissue + 108

Pandya et al. Raman Pancreatic tissue + 109

Hu et al. Raman Gastric tissue + 110

Maziak et al. FTIR Oesophageal tissue + 111

Xu et al. ATR-FTIR Gall bladder + 112

Kondepati et al. FTIR Pancreatic tissue + 113

Sun et al. FTIR Gastric tissue + 114

and dermatology are considered. In addition, first steps towards in vivo
applications are described [43].
The design of an auto-classifying system and its application in Raman spec-
troscopy diagnosis of gastric carcinoma was investigated by Tan et al. They
developed a tentative user-friendly system to auto-classify Raman spectra
of gastric carcinoma tissues. They also suggested that the software could be
applied into classification of other tissues with some necessary alterations [100].
S.-F. Weng et al. studied tumours from the stomach, small intestine, colon,
rectum, liver, and other parts of the digestive system, with FTIR fibre optics
and FT-Raman spectroscopic techniques. The spectra of samples were
recorded on a Magna750 FTIR spectrometer with a mercury cadmium tel-
luride (MCT) detector and mid-infrared optical fibre. The measurements
were carried out by touching the sample with an attenuated total reflectance
probe. FT-Raman spectra of the samples were recorded on a 950 FT-Raman
spectrometer. The results indicate that (i) the C=O stretching band of adipose
can be observed in some normal tissues but is rarely found in malignant tis-
sues, and (ii) the relative intensities I 1460 /I 1400 are high for normal tissue but
low for malignant tissue. For most normal tissues, the intensities for the 1250
cm −1 band are stronger than for band around 1310 cm −1 , while the 1310 cm −1
band in malignant tissues is often stronger than the 1250 cm −1 ba nd s [101].