Biomedical Engineering Reference
In-Depth Information
(a)
(b)
IM
20 µm
(c)
IM
1 µm
IM
(d)
IM
100 µm
FIGURE 5.5
Sr-HA implants after 28 days of implantation in animal model. (a) Histological sections revealed
mineralized bone growth in the medullary area along and in direct contact with surfaces was
observed (contact osteogenesis). (b, c) Backscatter scanning electron microscopy micrographs of
the implants after 28 days of healing. (b) Low-magnification image showing the implant, implant
surface, and bone tissue. Osteocyte lacunae and canaliculi were frequently observed close to
the implant surface. (c) Higher-magnification image showing direct contact was observed. (d)
Overlapped element maps of calcium (green), titanium (red), and oxygen (blue), showing bone
formation along the HAp-implant surface at 28 days healing. The enlarged surface oxide is
shown in purple (overlapped blue and red) along the implant perimeter.
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