Biomedical Engineering Reference
In-Depth Information
Table 1 (continued)
Bioprocess system
Key process parameters (CPPs) a
Calorimeter
model
Growth metabolism
Sensitivity
(mW L -1 )
Reference
50
Bench-scale Calorimetry
of Halomonas
elongata
2-L
Aerobic
Real-time monitoring of the critical process parameters by
biocalorimetry
[ 34 ]
bioreactor
Feedback control
BioRC1
Aerobic
5-8
Specific growth rate
[ 35 , 36 ]
Feedback control
20-L
bioreactor
Aerobic
Specific growth rate control in S. cerevisiae and E. coli cultures
to avoid production of overflow metabolites
[ 37 , 38 ]
a
Bioprocess parameter/anomalies monitored based on metabolic heat flow rate profile
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