Bioactive Glass-Based Coatings and Modified Surfaces: Strategies for the Manufacture, Testing, and Clinical Applications for Regenerative Medicine - Biological and Biomedical Coatings: Processing and Characterization - page 399

TABLE 9.11
Cellular Evaluation of Bioactive Glasses

Outcome

Viability/
Adhesion

Differentiation/
KeptPhenotype

Matrix
Synthesis Material Celltype Growth Mineralization Remarks Reference

BG disks Chondrocytes + + + + Collagen ibril in-growth into

surface reaction layers; HA
formation on surface

[3]

BG disks Osteoblasts + + + + [4, 5]

BG disks Osteoblasts + + + + + [29]

BG-P Osteoblasts + + + + + [29]

BG-E Osteoblasts + + + + + First indication of genetic

inluence of BG on cell cycle;
critical concentration of ionic
products needed for
osteostimuation

[6, 29]

BG-E mFLBs + + Critical concentration of ionic

products needed for
calciication

[7]

BG powders Osteoblasts + + + + [8]

Note: BG, bioactive glass; BG-E, bioactive glass extract (ionic product solution); BG-P, bioglass particles (90-710 μm); HA, hydroxyapatite.