Biomedical Engineering Reference
In-Depth Information
Definition 2.9
(continued)
Here
I
3
is the 3
denotes the Kronecker product [
16
].
The 1D derivative operators are defined by
×
3 identity matrix and
⊗
D
1
d
1
=
⊗
⊗
,
I
n
3
I
n
2
(2.35)
D
2
d
1
⊗
=
⊗
,
I
n
3
I
n
1
(2.36)
D
3
d
1
⊗
=
⊗
.
I
n
2
I
n
1
(2.37)
The
I
n
i
denote identity matrices with the size
n
i
, and the
n
i
defined according to Definition
2.8
. The discrete 1D first derivative operators
for each dimension are defined by
n
i
×
,
i
∈{
1
,
2
,
3
}
⎡
⎤
−
11
0
⎣
⎦
∈
R
.
.
.
.
.
.
n
i
−
1
,
n
i
d
i
1
=
,
i
∈{
1
,
2
,
3
} .
(2.38)
−
0
11
The analog of the above definition in image space is given with the following
Definition
2.10
. As the real displacements and not the corresponding coefficients are
processed, this version is even more related to the diffusion regularization energy in
Definition
2.3
.
Definition 2.10 (Tikhonov regularization (image space)).
Let the number
n
1
n
2
n
3
3
of spline coefficients be
n
=(
,
,
)
∈
N
and
b
i
(
x
)=
b
(
x
−
i
)
for
i
∈
n
d
{
, be the translated spline basis function
b
defined in
Eq. (
2.27
). The
Tikhonov regularization
matrix in image space is defined as
1
,...,
}
,
d
∈{
1
,
2
,
3
}
M
ti
T
3
T
2
T
1
=
I
3
⊗
⊗
⊗
.
(2.39)
n
d
,
n
d
The matrices
T
d
∈
R
are defined by
T
i
,
j
=
d
∂
b
i
(
x
)
·
∂
b
j
(
x
)
dx
,
d
∈{
1
,
2
,
3
} ,
(2.40)
Ω
n
d
n
d
d
where
i
∈{
1
,...,
}
,
j
∈{
1
,...,
}
, and
Ω
⊂
R
is the 1D subspace of
Ω
in dimension
d
∈{
1
,
2
,
3
}
.
(continued)
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