Biomedical Engineering Reference
In-Depth Information
The deformation u is represented by a projection of the spline coefficients, given by
the parameter vector p , into the image space by the projection matrix Q
u
=
Q
·
p
.
(2.30)
For the hyperelastic regularization the transformation y is first determined according
to Eq. ( 2.29 ) and is then regularized as described in Eq. ( 2.17 ). The regularization
functional in Eq. ( 2.28 ) is then defined as
hyper
S M (
p
)
:
= S
(
x
+
Q
·
p
) .
(2.31)
2.1.3.2
Coefficient-Based Regularization
The regularization term
in Eq. ( 2.28 ) is based on the coefficient vector p in
the case of coefficient-based regularization and is a weighted norm of the form
S M (
p
)
2
M :
p T Mp
S M (
p
)
:
=
p
=
.
(2.32)
The matrix M determines the regularization type. Instead of regularizing the
deformation u p (
3 as in the non-parametric case
(cf. Sect. 2.1.2 ) we now regularize directly on p . We speak of coefficient-based
regularization in image space if the regularization on p considers the projection
matrix Q and thus regularizes Q
x
for each spatial position x
)
R
p . If only p is taken into account we speak of
coefficient-based regularization in coefficient space .
With Tikhonov regularization we will discuss one option for coefficient-based
regularization in coefficient space. Tikhonov regularization punishes gradients in
the spline coefficients and is the coefficient-based analog of diffusion regularization
introduced in Definition 2.3 .
·
Definition 2.9 (Tikhonov
regularization
(coefficient
space)).
Tikhonov
regularization in coefficient space is defined by the choice of
M tc
D T D
=
(2.33)
in Eq. ( 2.32 ). The superscript tc denotes
(
t
)
ikhonov in
(
c
)
oefficient space. D
is defined by
D 1
D 2
D 3
.
D
=
I 3
(2.34)
(continued)
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