Biomedical Engineering Reference
In-Depth Information
The deformation
u
is represented by a projection of the spline coefficients, given by
the parameter vector
p
, into the image space by the projection matrix
Q
u
=
Q
·
p
.
(2.30)
For the hyperelastic regularization the transformation
y
is first determined according
to Eq. (
2.29
) and is then regularized as described in Eq. (
2.17
). The regularization
functional in Eq. (
2.28
) is then defined as
hyper
S
M
(
p
)
:
=
S
(
x
+
Q
·
p
)
.
(2.31)
2.1.3.2
Coefficient-Based Regularization
The regularization term
in Eq. (
2.28
) is based on the coefficient vector
p
in
the case of coefficient-based regularization and is a weighted norm of the form
S
M
(
p
)
2
M
:
p
T
Mp
S
M
(
p
)
:
=
p
=
.
(2.32)
The matrix
M
determines the regularization type. Instead of regularizing the
deformation
u
p
(
3
as in the non-parametric case
(cf. Sect.
2.1.2
) we now regularize directly on
p
. We speak of coefficient-based
regularization in
image space
if the regularization on
p
considers the projection
matrix
Q
and thus regularizes
Q
x
for each spatial position
x
)
∈
R
p
. If only
p
is taken into account we speak of
coefficient-based regularization in
coefficient space
.
With Tikhonov regularization we will discuss one option for coefficient-based
regularization in coefficient space. Tikhonov regularization punishes gradients in
the spline coefficients and is the coefficient-based analog of diffusion regularization
introduced in Definition
2.3
.
·
Definition 2.9 (Tikhonov
regularization
(coefficient
space)).
Tikhonov
regularization
in coefficient space is defined by the choice of
M
tc
D
T
D
=
(2.33)
in Eq. (
2.32
). The superscript tc denotes
(
t
)
ikhonov in
(
c
)
oefficient space.
D
is defined by
⎡
⎤
D
1
D
2
D
3
⎣
⎦
.
D
=
I
3
⊗
(2.34)
(continued)
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