Biomedical Engineering Reference
In-Depth Information
Table 1
Various viral and non-viral based nanocages for theranostic applications
Nanocages
Therapeutic agent
Imaging agent
Model system
References
PTX
(NIR) luorescent dye
ICG-Der-02
MDA-MB-231 tumor-bearing
mice
Shan et al. (2012)
Folate modiied adenovirus
Dox
Alexa Fluor 488
Huh-7 cells, Suit-2 and
HepG2 cells
Toita et al. (2013)
HspG41C
Biotinylated DNA binding
protein
Photosensitizer (SnCe6)
Alexa Fluor 488
A. actinomycetemcomitans
bioilm
Suci et al. (2010)
Dox
Alexa Fluor 532
KB, A549, and HeLa cells
Ren et al. (2013)
PEG or folic acid conjugated
E2 subunit of pyruvate
dehydrogenase
Dox
Alexa Fluor 532
MDA-MB-231 cells
Ren et al. (2011)
E2 subunit of pyruvate
dehydrogenase
Targeting peptide
(CD 46, RME-F, IBDR)
conjugated red clover necrotic
mosaic virus
Dox
Fluorescein and rhodamine
HeLa cells
Lockney et al. (2011)
Porphyrin
GFP
CHO cells stably expressing
human CD22 (CHO-CD22
+
)
and Flp-In-CHO cells
(CD22-negative)
Rhee et al. (2012)
Glycan targeted
bacteriophage Q
ʲ
Bacteriophage Q
ʲ
Human epidermal growth
factor (EGF)
Alexa Fluor 488
A431 cells
Pokorski et al. (2011)
Recombinant polyoma
virus-like particles
MTX
GFP
Swiss mouse ibroblasts
(Swiss 3T3), human T cell
leukemia line CCRF-CEM,
MTX transport-resistant
CCRF-CEM/MTX cells
Abbing et al. (2004)
Antisense oligodeoxynucleo-
tides (ODNs)
FITC
HL-60 cells, RAW264 cells
Wu et al. (2005)
MS2 bacteriophage
(continued)
