Information Technology Reference
In-Depth Information
s
DC
ij
=
s
ij
for
n
=0
to
N
DC
m
processes
a
DC
nm
for
p
to
P
compute
o
p
o
p
(
m
)=
o
p
(
m
)+
o
p
if
o
0
(
m
)
>t
m
DC
m
removed from population
DC
m
migrate to Lymph node
l++
analyse antigen and calculate MCAV
3.5
Lymph Node and Antigen Aggregation
Once
DC
m
has been removed from the population, the contents of
a
D
n
and
values
o
pm
are logged to a file for the aggregation stage. Once completed,
s
DC
ij
,
a
D
n
and
o
pm
are all reset, and
DC
m
is returned to the sampling population. The
re-cycling of DCs continues until the stopping condition is met (
l
=
L
). Once
all data has been processed by the DCs, the output log of antigen-plus-context
is analysed. The same antigen is presented multiple time with different context
values. This information is recorded in a log file. The total fraction of mature
DCs presenting said antigen (where
o
1
> o
2
) is divided by the total amount of
times the antigen was presented namely
o
1
/
(
o
1
+
o
2
) . This is used to calculate
the
mean mature context antigen value
or MCAV.
3.6
Signals and Antigen
An integral part of DC function is the ability to combine multiple signals to
influence the behaviour of the cells. The different input signals have different
effects on cell behaviour as described in Section 2. The semantics of the different
category of signal are derived from the study of the influence of the different
signals on DCs
in vitro
. Definitions of the characteristics of each signal cate-
gory are given below, with an example of an actual signal per category. This
categorisation forms the signal selection schema.
-
PAMP -
s
i
0
e.g. the number of error messages generated per second by a
failed network connection
1. a signature of abnormal behaviour e.g. an error message
2. a high degree of confidence of abnormality associated with an increase
in this signal strength
-
Danger signal -
s
i
1
e.g. the number of transmitted network packets per second
1. measure of an attribute which significantly increases in response to ab-
normal behaviour
2. a moderate degree of confidence of abnormality with increased level of this
signal, though at a low signal strength can represent normal behaviour.
