Brachytherapy for Nanoscale Cancer Therapy Using Radioisotopes - Atomic Nanoscale Technology in the Nuclear Industry - page 85

8
BrachytherapyforNanoscaleCancer
Therapy Us ingRadioisotopes
TaehoWoo
CONTENTS
8.1. Introduction................................................................................................... 85
8.2. Method.and.Results..................................................................................... 87
8.3. Conclusions................................................................................................... 88
References............................................................................................................... 88
8.1 Introduction
There.are.four.kinds.of.brachytherapy:.high-dose-rate.(HDR),.medium-dose-
rate.(MDR),.low-dose-rate.(LDR),.and.pulse-dose-rate.(PDR).methods..HDR.
brachytherapy.protocol.has.been.developed.for.nanoscale.treatment.(Korean.
Food. and. Drug. Administration. [KFDA]. 2004).. The. object. of. this. project. is.
the.establishment.of.safety.and.accuracy.standards.for.the.HDR.treatment.
system,.which.includes.the.HDR.afterloader,.source,.and.radiotherapy.treat-
ment. planning. (RTP).. There. are. many. functional. and. structural. features,.
such.as.the.structure.of.a.source,.source.dwelling.method,.safety.interlock.
feature,. and. dose. calculation. accuracy,. which. are. unique. for. each. model..
It.is.necessary.for.the.different.features.of.the.HDR.treatment.system.to.be.
evaluated. by. a. standardized. criterion. in. order. to. be. approved. for. patient.
treatment. (AAPM. [American. Association. of. Physicists. in. Medicine]. 1994,.
1995,. 1997;. IAEA. [International. Atomic. Energy. Agency]. 2000;,. Khan. 2003;.
Van. Dyk. 1999).. Table 8.1. shows. the. acceptable. physical. application. sites. of.
brachytherapy.with.respect.to.patient.sex..Table 8.2.lists.the.sampled.radio-
isotopes.in.clinical.usage..It.is.important.to.accurately.calculate.dosage.for.
patient. therapy. in. clinical. applications.. The. automatic. calculator. is. devel-
oped.using.commercial.software..It.is.quite.exact.in.RTP..The.clinical.result.
is.matched.with.the.calculations.by.comparison.
Hrycushko.et.al..(2011).studied.brachytherapy.in.lumpectomy.focal.treat-
ment.. Postoperative. radiotherapy. has. commonly. been. used. for. early-stage.
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