Environmental Engineering Reference
In-Depth Information
7
MeasurementProilesofNanoscaleIonBeam
for
Optimiz
edRadiationEnergyLosses
TaehoWooandHyosungCho
CONTENTS
7.1. Introduction................................................................................................... 75
7.2. Method........................................................................................................... 76
7.3. Results............................................................................................................ 77
7.4. Conclusions................................................................................................... 81
References............................................................................................................... 83
7.1 Introduction
The.ion.beam.is.used.to.treat.regions.of.interest.in.organ.material.(Fukumura.
et.al..1998,.Iseki.et.al..2003,.Rebisz-Pomorska.et.al..2010)..This.chapter.inves-
tigates.the.behavior.of.nanoscale.ions.with.respect.to.their.interaction.with.
cancer.cells..The.optimized.dose.is.classiied.according.to.several.variables.
such.as.beam.energy,.cell.properties,.cancer.cell.depth,.and.so.on..Successful.
treatment.is.expected.in.clinical.results..It.is.important.to.make.the.spread.
out.Bragg.peak.for.the.therapeutic.radiation.distribution..Pristine.peaks.are.
summed. to. reveal. the. optimized. broad. shape.. The. purpose. of. the. beam.
shapes.is.to.it.the.target.area..It.is.important.to.shape.to.match.the.dimen-
sions. of. the. tumor,. and. thus. deliver. most. of. the. radiation. to. the. targeted.
tumor. mass,. not. to. the. surrounding. normal. tissue.. For. this. purpose,. it. is.
necessary.to.produce.several.ion.beams..Although.this.is.a.simple.method,.
the.cost.of.ion.beam.production.will.increase..In.this.chapter,.the.character-
istics. of. ion. beams. are. classiied. by. ionizations,. energy. to. recoil,. and. pho-
nons.. This. chapter. discusses. a. radiation. therapy. protocol. using. the. Bragg.
peak.where.computerized.simulations.are.performed.with.Stopping.Range.
of.Ions.in.Matter.(SRIM).2008..The.results.are.calculated.simply.and.cheaply.
using.the.SRIM.2008.computational.code.
The.Bragg.peak.is.examined.with.respect.to.several.variables..Analysis.of.
computational.simulations.is.of.importance.before.construction.of.a.facility.
due.to.the.size.required.and.the.high.cost.of.installation..The.SRIM.2008.code.
75
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