Biomedical Engineering Reference
In-Depth Information
5.4.3.2 M-Step
The M-step estimates the posterior probability
p
(
A c |
y k )
. Using the same arguments
as in Sect. 5.3.2.2 ,wehave
log
p
(
A c |
y
)
E z log p
A c ) =
E z log p
A c )
=
(
y
,
z
,
(
y
|
z
,
A c ) +
log p
(
z
) +
log p
(
K
=
E z
log p
(
y k |
z k ,
A c ) +
log p
(
A c )
k
=
1
K
M
1
2
1
2
T
a j ʻ j ʱ
,
=
E z
1 (
y k
Au k
B
v k )
ʛ (
y k
Au k
B
v k )
a j
k
=
j
=
1
(5.121)
where z collectively expresses z 1 ,...,
z K , and terms not containing A are omitted.
The form of the posterior distribution in Eq. ( 5.44 ) is also assumed:
M
a j ,(ʻ j ʨ ) 1
a j | ¯
p
(
A c |
y
) =
p
(
A
|
y
) =
1 N(
).
j
=
¯ A is obtained as the A that makes
The mean
A log
p
(
A
|
y
)
equal to zero, and the
precision
as the coefficient of a j in that derivative. Using Eqs. ( 5.65 ) and ( 5.66 )
the derivative is computed as
ʻ j ʨ
K
u k
(
|
y k ) =
ʛ
1 (
y k
Au k
v k )
ʛ
ʱ
A log
p
A
E z
B
A
k
=
= ʛ
R yu ʛ
BR v u ʛ
A
(
R uu + ʱ ).
(5.122)
In Eq. ( 5.122 ), the coefficient of a j is
ʻ j (
R uu + ʱ )
, and thus the matrix
ʨ
is equal
to
ʨ =
R uu + ʱ ,
(5.123)
¯ A is obtained as
and
¯ A
) ʨ 1
= (
R yu
BR
,
(5.124)
v
u
where R yu is obtained as
K
u k .
R yu =
y k ¯
(5.125)
k
=
1
 
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