Chemistry Reference
In-Depth Information
S
H
N
H
CF
3
N
NMe
2
NO
2
(
R
)-
153
(2 mol %)
Benzene, 25°C
NO
2
+
R
NO
2
Ar
R
NO
2
Ar
23
R=Et,
n
-Pr
60A
152
74:26-90:10 dr, 91-95% ee, 55-94% yield
Scheme 2B.34.
CF
3
O
F
3
C
S
O
N
HN
MeO
R
O
N
O
R
153A
(5 mol %
)
OH
OMe
91-98% ee
88-97% yield
R'
O
R'
n
n
MeOH, Et
2
O, rt
R
O
R
O
28
29
O
S
O
N
HN
MeO
N
O
O
153B
(10 mol
%)
NO
2
COOMe
+
R
R
COOMe
Ar
CH
2
Cl
2
, -40°C
Ar
NO
2
60A
45
154
3.1:1-50:1 dr
90-96% ee
71-99% yield
Scheme 2B.35.
89
