Biomedical Engineering Reference
In-Depth Information
Remove of
template
TEOS
QDs
QDs
Recognition of
analyte
QDs
QDs
Figure 11.20
Schematic procedures for the preparation of DPA-MIP-QDs sensor [48].
0.015 μM. h e sensor has been successfully applied to determine the
TBBPA in water and soil samples, and the average recoveries of the TBBPA
at various spiking levels ranged from 80.2% to 96.5% with relative standard
deviation below 8.0%. h e results provided a clue to develop sensors for
rapid determination of hazardous materials from complex matrixes.
Liu
et al.
also reported a novel dual-function material by anchoring a
MIP layer on CdTe/ZnS QDs using a sol-gel with surface imprinting [49].
h e material exhibited highly selective and sensitive determination of rac-
topamine through spectrol uorometry and solid-phase extraction coupled
with HPLC. A series of adsorption experiments revealed that the material
showed high selectivity, good adsorption capacity and a fast mass transfer
rate. Fluorescence from the MIP-coated QDs was more strongly quenched
by ractopamine than that of the non-imprinted polymer, which indicated
that the MIP-coated QDs acted as a l uorescence sensing material could
recognize ractopamine (Figure 11.21). In addition, the MIP-coated QDs
as a sorbent was also shown to be promising for Solid Phase Extraction
coupled with HPLC for the determination of trace ractopamine in feeding
stuf s and pork samples. Under optimal conditions, the spectrol uorome-
try and Solid Phase Extraction-HPLC methods using the MIP-coated QDs
had linear ranges of 5.00×10
-10
-3.55×10
-7
and 1.50×10
-10
-8.90×10
-8
mol
L
-1
, respectively, with limits of detection of 1.47×10
-10
and 8.30×10
-11
mol
L
-1
, the relative standard deviations for six repeat experiments of ractopa-
mine (2.90×10
-9
mol L
-1
) were below 2.83% and 7.11%.
Fan
et al.
reported for the i rst time a chemical method to prepare gra-
phene quantum dots (GQDs) from Graphene Oxide [50]. Water soluble
and surface unmodii ed GQDs, serving as a novel, ef ective and simple
