Chemistry Reference
In-Depth Information
N
O
N
+
H
2
N
O
NH
2
F
F
O
O
O
-
O
O
-
O
HO
HO
HO
N
HO
C
O
HO
O
Rhodamine
S
O
AlexaFluor 488
FITC
Oregon green 488
O
O
O
O
NH
2
Et
O
O
NH
N
O
-
Na
+
NH
N
N
S
O
O
S
N
N
O
-
Na
+
N
NHN
NHN
H
H
2
N
H
O
O
O
Congo red
HPPH
Porphyrin
SO
3
Na
SO
-
SO
-
SO
-
NaO
3
S
O
-
O
3
S
SO
-
+
N
N
+
N
N
SO
3
Na
O
OH
O
Cy5.5
800 CW
OH
FIgure 15.11
Representative fluorescent dyes that have been used for the development of dual-modality imaging agents.
O
HO
OH
OH
N
N
O
O
HO
N
OH
N
N
O
O
N
N
O
OO
O
HO
OH
OH
OH
DOTA
DTPA
O
O
O
OH
OH
OH
N
HO
N
N
N
N
O
O
OH
HO
N
O H
HO
O
O
NOTA
TTDA
FIgure 15.12
a selected list of chelators that have been used for the development of dual-modality imaging agents.
