Chemistry Reference
In-Depth Information
O
R
1
N
O
R
3
C
O
R
4
R
1
HO
+
N
+
R
3
R
4
NH
H
H
NH
2
R
2
R
2
.
Thiol chemistry
O
O
R
2
S
R
2
SH
R
1
Maleimides
+
N
N
R
1
O
O
S
S
R
3
S
R
3
Thiol-disul�de exchange
SH
+
R
1
+
R
2
R
1
S
R
2
SH
Click chemistry
N
-
R
3
N
Cu (I)
R
1
NN
N
+
+
R
2
N
R
1
R
2
R
3
Schiff base formation + reduction
O
Reducing agent
N R
2
HN R
2
R
1
+ H
2
N R
2
R
1
R
1
H
Boronic acids complex formation
OH
B
R
3
R
3
HO
O
HO
OH
B
-
R
2
+
R
2
O
HO
R
1
R
1
Carbodiimidazole medicated esteri�cation
O
O
R
2
N
+
HO
R
2
R
1
O
N
R
1
Mannich condensation
R
1
HO
R
1
HO
O
+
NH
2
+
N
HO
R
2
HH
HO
R
2
Imidoamide formation
NH
NH
+
R
1
R
2
R
1
R
2
N
H
2
N
O
H
FIgure 9.10
some of the most common chemical reactions used for the functionalisation of nanoparticles.
