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0
10
20
30
40
50
-0.052
-0.045
-0.039
-0.032
-0.028
-0.019
-0.013
-0.006
0.000
0.008
0.013
0.019
0.026
0.032
0.039
0.045
0.052
0.058
0.064
0.071
0.077
0.084
0.090
0.097
0.103
0.110
0.116
0.129
*
***
* ** **
****
********
**********
*****************
**********************
***************************
*
**********************************
*******************************************
********************************************
**************************************
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**********************
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***********
****
* **
*
** ******* ***** ****** *******
* *
FIGURE 1 Histogram of Bootstrap Replications for Gregory's Rule. The his-
togram summarizes the 400 bootstrap replications of R* that are used in estimat-
ing the expected excess error of Gregory's rule for predicting death in chronic
hepatitis. Values of R* range from -0.045 to 0.116, with mean 0.039, standard
deviation 0.027, and quantiles R (.05) =-0.006 and R (.05) = 0.084.
(
*
) ==
ˆ
ˆ
ˆ
ˆ ,
ERFFr
,
r
ˆ
*
~ ˆ
boot
FF
and variance, say, s 2 . Figure 1 shows that this population is close to
normal, so
ˆ
ˆ
12
r
r
2
s
400
,
400
with high probability. Approximating s 2 with
400
1
400
* -
2
[
] = (
2
 Rr
)
ˆ
ˆ
s 400
2
=
0 027
.
b
400
-
1
b
-
1
gives
(
)
ˆ
ˆ
12
r
r
2 0 027
.
400
=
0 0027
.
;
400
r
r
r
so with high probability, 400 is within 0.0027 of =
boot .
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