Biomedical Engineering Reference
In-Depth Information
Table 6.2
Cross-correlation coefficients obtained from (A) different
tracks of a single averaged
x-z
scan and (B) population
result from three different cats
Correlation between fOCT and unit profiles (A)
Site #
Correlation coeff. for 0-90 deg
Correlation coeff. for 45-135
#1
0.94
0.66
#2
0.809
0.764
#3
0.908
0.926
#4
0.852
0.899
#5
0.348
0.374
#6
0.751
0.365
(B)
Cat #
# of sites that show significant correlation
(p
<
0.005)
C
-22
4/8
C
-30
9/11
C
-36
5/11
7. fOCT - Future
Prospects
It should be mentioned that in the comparison study discussed in
the previous section, different methods of OISI, fOCT and MUA
were conducted independently to be compared later. However,
there could be some spatial ambiguity of 100
mormorein
such comparisons. For more reliable comparisons, it may be nec-
essary to conduct simultaneous measurements of OISI, fOCT and
MUA. In addition, recently, we have started the implementation
of a high speed Fourier domain OCT system that would largely
improve the sensitivity of OCT signal enabling a clearer picture
of the columnar organization of orientation columns in cat visual
cortex.
Recently, we have also started applying fOCT to the study
of the rat olfactory system and our preliminary results show
clear odor-dependent responses. We therefore expect this method
to provide novel insights regarding the response distribution in
granule cell layers that receive input from olfactory glomeruli and
lie deeper from superficial regions of the bulb.
μ
