Biomedical Engineering Reference
In-Depth Information
(
a
)
(
b
)
(
c
)
Figure 12.12 (a)
Schematic representation of MPTS modii cation of silica nanoparticles,
(b) prearrangement of MSM and MAA, and (c) preparation of SiO
2
@MSM-MIP
nanoparticles (Reproduced with permission from [31]).
can be achieved by the molecular imprinting modii cation at the surface of
silica nanoparticles.
Surface imprinting over nanosized support materials is particularly
suitable for protein templates, considering the problems with mass trans-
fer limitation and low binding capacity [32]. Recently, Chen
et al.
studied
the synthesis process toward enhancement of the imprinting performance
