Biomedical Engineering Reference
In-Depth Information
6.9
A research group worked on using a novel surface treatment method to en-
hance surface hydrophilicity. How would they know if the surface was indeed
chemically modified by the plasma treatment?
6.10
BioX has developed a new prosthetic device but they do not know how to ster-
ilize it. They want a summary of different available options so that they can
compare methods. Please summarize different available options while high-
lighting the deciding factor.
6.11
What differentiates biomaterial-centered infections from the common
infections?
6.12
State two main differences between material selections for manufacturing a
prosthetic device and tissue engineering scaffold.
6.13
Describe different processing techniques available for generating porous
structures.
References
[1]
Williams, D. F.,
Defi nitions in Biomaterials
, New York: Elsevier, 1987.
[2]
Protek, AG, Technical brochure, Switzerland, 1994.
[3]
Schoen, F. J., and R. J. Levy, “Tissue Heart Valves: Current Challenges and Future Research
Perspectives,”
J. Biomed. Mater. Res.
, Vol. 47, 1999, pp. 439-465.
[4]
The Center for Disease Control and Prevention, http://www.cdc.gov/ncidod/dhqp/
bp_sterilization_medDevices.html.
[5]
Ratner, B. D., et al.,
Biomaterials Science,
2nd ed., San Diego, CA: Academic Press, 2004.
[6]
Yan, J. M., and H. T. Lin, “Wettability and Protein Adsorption on HTPB-Based Polyure-
thane Films,”
Journal of Membrane Science
, Vol. 187, No. 1-2, 2001, pp. 159-169.
[7]
Kaelble, J., “A Surface Energy Analysis of Bioadhesion,”
Polymer
, Vol. 18, 1977, p. 475.
[8]
Lawrence, J., et al., “A Two-Stage Ceramic Tile Grout Sealing Process Using a High Power
Diode Laser-Grout Development and Materials Characteristic,”
Optics and Laser Technol-
ogy,
Vol. 30, No. 3, 1998, pp. 205-214.
[9]
Wang, X. H., et al., “Improvement of Blood Compatibility of Artifi cial Heart Valves Via
Titanium Oxide Film Coated on Low Temperature Isotropic Carbon,”
Surface and Coat-
ings Technology
, Vol. 128-129, 2000, pp. 36-42.
[10]
Gristina, A. G., “Biomaterial-Centered Infection: Microbial Adhesion Versus Tissue Inte-
gration,”
Science
, Vol. 237, No. 4822, 1987, pp. 1588-1595.
[11]
Hao, L., and J. Lawrence, “CO
2
Laser Induced Microstructural Features in a Magnesia
Partially Stabilised Zirconia Bioceramic and the Effects Thereof on Wettability Character-
istics,”
Materials Science and Engineering: A Structural Materials: Properties, Microstruc-
ture and Processing,
Vol. 364, 2003, pp. 171-181.
[12]
Hao, L., J. Lawrence, and L. Li, “The Wettability Modifi cation of Biograde Stainless Steel
in Contact with Simulated Physiological Liquids by the Means of Laser Irridation,”
Ap-
plied Surface Science
, Vol. 247, No. 1-4, 2005, pp. 453-457.
Selected Bibliography
Dee, K. C., et al.,
An Introduction to Tissue-Biomaterial Interactions
, New York: John Wiley &
Sons, 2002.
