Chemistry Reference
In-Depth Information
Theophylline
Anti-asthmatic.agent.
(methyl-xanthine.rel..
o - Caffeine )
(a).C/PO.(+ n -CoPC)
(b).C/PO.(+K 2 PtCl 6 )
(a).CV,.DPV
(b).AD-LC
Study.on.catalytic.effect.and.formation.of.
three.metabolites;. E A .=.+0.17.V.vs..ref.
LODs:.1.1.μg.L −1 .(Thp),.11.μg.L −1 .(mbs)
(a).Drug,.tea.extract
(b).Serum,.black.tea
(a).[932]
(b).[2626]
Thioridazine
Antidepressant.drug.(tricyclic.
heteroder.)
C/PO.(+b-CD)
CV,.DPV
Inclusion.(“host-guest”).accum..Effect.by.
cyclodextrin;.lin.:.nM;.also.simult..detn..
with. Imipramine, Trimipramine
pharm..forms.(com..
tablets)
[1412]
Thymol
Disinfectant.agent.
(isopropyl- m -cresol)
GC/Nj.(unm.)
DPV,.
AD-HPLC
GC:.glassy.carbon.powder,.s.e.:.BR-B.+.
MeOH.(90%.v/v;.pH.7),. E A .=.+1.1.V.vs..
ref.;.LOD:.3.×.10 −7 .M;.wall-jet.conf.
Pastilles.
( Septolete ® ),.
thyme.syrup
[2627]
Tiluadome
Analgeticum.(opiod.
benzodiazepine.der.)
C/PO.(+“C-18”)
CV,.DPV
modif.:.com..ion-pair/exchange.resin
o.c.,.BR-B.(pH.6),.2.×.10 −7 -5.×.10 −6 .M;.
studies.on.adsor.;.no.sample.treatment
Model.sample.
(spiked.urine)
[1809]
Tizanidin
Muscle.relaxant.
benzothiazole gr.)
C/Nj.(unm.;. Metrohm )
CV,.COU,.
DPV
Study.on.irrev..oxidn;.e.:.PhB.+.MeOH.
(pH 7);.lin.r..2.×.10 −5 -1.×.10 −4 .M.(DPV)
Model.solns.
[2628]
Todralazine .
(hydrochloride)
Antihypertensive. a ..(subst..
phthalazine-hydrazine.der.)
C/Nj.(+silica.gel)
CV,.DPV
o.c.,.pH.1.8.(0.1.M.KNO 3 ),.3.×.10 −8 .M;.
studies.on.adsor..mechanism,.modif.
Model.solns.,.
human.urine
[1152]
Tramadol .
hydrochloride)
Analgesic,.severe.pain.
reliever.(synth..der..from.
Opioid .group.)
C/NPOE.(+Tr-.PW 3 O 12 )
C/-”-.[+Tr-H 3 (SiMo 12 )].
[CP-ISEs]
POT.(dir.)
Ion-association.and.chem..equilibrium
NPOE:.nitrophenyl-octyl.ether;. t R .<.5.s,.
lin.r.:.6.×.10 −6 -0.1.M;. R R .=.90%-95%
pharm..forms,.milk,.
human.urine
[2629]
s-Trandorapril
Antihypertensive. a ..
(subst.  N -indol.carboxylic.
acid.alkylester)
C/PO.(+AAOd)
AD-SIA
modif.:.l-aminoacid.oxidase;.enantio-
selectivity.principles;.pH.6.8-7.4;.lin..
range:.0.001-100.μM
Model.samples.
(quality.control)
[747]
Trazodone .
(hydrochloride)
Antidepressant.(piperazinyl]-
propyl-1,2,4-triazol-
pyridine)
C/PO.(unm.)
CV,.COU,.
DPV
Study.on.pH,.pK i ,.k s .(for.irrev..oxidn),.
form..of.metabolites;.lin.range:.1.×.10 −6 -1.
×.10 −4 .M.(for.DPV.mode)
Model.solns.
[2630]
Triluperazine
Antipsychotic.drug.
(phenothiazine.der.)
C/PO.(unm.)
DPV,.CP,.CM
o.c.,.0.02-1.μg.mL −1 ;.LOD:.5.ng.mL −1 .
studies.on.adsor..accum..mechanism
Dosage.forms..
(tablets)
[731,2537]
Trimipramine
Antidepressant.(subst..
dibenzoaze-.pine.
propanamine)
(a).C/PO.(unm)
(b).C/Nj.(+β-CD)
DPV
Inclusion.(host-guest).effect.by.CD.(b)
LODs:.(a).1-2.5.×.10 −8 .M,.b).nM.level;.
study.focused.on.statistical.data.evaln.
Model.solns.
(a).[2631]
(b).[1412]
( continued )
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