Electroanalysis with Carbon Paste–Based Electrodes, Sensors, and Detectors - Electroanalysis with Carbon Paste Electrodes - page 322

TABLE 8.14 (continued)
Determination of Pharmaceuticals and Drugs at Carbon Paste Electrodes, Sensors, and Detectors: Survey of Methods and Selected Studies

Analyte
(Chemical
Form)

Classiication (Chem.
Speciication)

Type of CPE (Modiier)/
[Coniguration]

Technique
(Mode)

Experimental and Electroanalytical
Characterization, Selected Data; Notes Sample(s) Ref(s)

Sparloxacin Antibacterial.agent.

(luoroquinolone.de.)

(a).C/PO.(unm.,.+β-CD)
(b).C/PO.(unm.)

CV,.DPV (a).CD:.cyclodextrin;.acc..Mechanism.lin.:.

0.04-60.μM;.(b).r.:.2.×.10 −7 -6.×.10 −5 .M;.
simult..detn..with.Gaf.and.Lof

pharm..forms,.
diluted.urine

(a).[1417]
(b).[678]

Spiperon Antidepressivum.ag..

(luoro-alkylketone)

C/PO.(unm) CV,.DPV Study.on.irrev..oxidn..and.adsorption;.s.e.:.

0.1.M.H 2 SO 4 ,.LOD:.1.×.10 −6 .M

pharm..forms. [242]

Spiroplatin Antitumor.drug.[platinum(II).

der.]

C/Nj.( Metrohm ) CV,.DPV Study.on.electrode.oxidn..and.redn.,.incl.

SEM;.sub-millimolar.level.of.analyte

Model.solns. [2623]

Streptomycin Antibioticum.(from.

Streptomycin .sp.)

C/Nj.(+RuO 2 ).[ft-D] CV,.LC-EC 1.×.10 −6 -.0.001.M;.studies.on.catalytic.

effect,.CP-support.compr..with.GEE

Model.solns. [1219]

Sumatriptan .
(succinate)

Anti-migraine.agent.
(Me 2 -amino-Et-indol.
methan-sulfonamide)

C/Nj.(unm.) COU Studies.on.electrode.reaction.and.evaln..of.

n(e − );.“giant”.CPE.(Ø.=.20.mm),.detn..
with.GC-D.(in.LC-EC.mode)

Pure..preps..
(dosage tablets)

[206]

Tamoxifen .
(citrate)

Anti-breastcancer.ag..
(di-Ph-PhO- N,N ′-di-methyl-
ethanamine)

C/PO.(unm.) LSV,.2nd.

DeLV

Study.on.irrev..oxidn.,.AcB.+.MeOH.
(15%v),. |E A | .=.+1.1.V.vs..SCE;.lin.r.:.7.×.
10 −10 -3.×.10 −8 .M;.RSD.<.3%

pharm..forms..
(com. tablets)

[2624]

Tanshinone II-A Anti-atherosclerotic.a..(trad..

nat..Chinese.d.)

C/PO.(unm.) CV,.2nd.

DeLSV

Study.of.rev..eld..reaction.(via:.e − +.H + )
s.e.:.BR-B.+.EtOH.(40%.v/v;.pH.2.4);
lin.:.1.×.10 −8 -2.×.10 −7 .M;.CP:.mech.rgnt

pharm..forms..
(pills Danshen ® )

[2625]

Tenoxicam Antiinlammatory.a..(subst..

thiazinecarbo-.xamide.
dioxide)

C/PO.(unm;.+fatty.acids) CV,.DPAdSV 0.1.M.BR-buff.,.LOD:.1.nM;.adsor.,.modif.,.

and.interfs..studies.(AA,.UA)

Model.solns. [2616]

Tetracycline Tetracycline.antibiotic.(from.

Streptomyces .sp..antibiotic.
group)

(a).C/PO.[+dsDNA.+.
Cu 2+ ]
(b).C/PO.(+Cel/dsDNA)

(a).DPASV
(b).AD-CE

(a,b).Interaction.with.dsDNA/cellulose.+.
Cu 2+ ,.LODs:.1-5.nM;.simult..detn..with. C
hlortetracycline , Oxytetracycline .and.
Doxycycline ;.(b).on-chip.μ-detector

(a).Test.solns..
(in AcB)
(b).Beef.meat

(a).[2538]
(b).[562]