Chemistry Reference
In-Depth Information
s-Flurbiprofen
Antiinlammatory.d..
(aryl-propionic.acid)
(a,b).C/Nj.(
α
,.
β
,.
γ
.
subst-CDs)
(c).C/Nj.(+
two diff
..
mcAbs).[CP-ESE]
POT,.(dir.)
(a,b).accum..via.inclusion.and.chiral.effect.
by.cyclodextrins;.subst.:.HO-N(Me)
3
,.
LODs:.1-10.×.10
−9
.M
(c).mdf:.macrocyclic.antibiotics.
(ch. selectors)
(a,b).pharm..
product.(tablets.
Froben
®
)
(c).Raw.product.
(drug)
(a).[2568]
(b).[2569]
(c).[2570]
Gatiloxacin
Antibacterial.agent.
(luoroquinoline.der.)
(a).C/PO.(unm.)
(b).C/PO.
(+.
β
-cyclodextrin)
CV,.DPV
(a).simult.detn..with.
Lof
.+.
Spf
,.(b).with.
Lof, Nof
,.and.
Ol
.;.(a).LOD:.1.×.10
−7
.M
(b).LOD:.2.×.10
−8
.M,.s.e.:.BRB.(pH.4.0)
Dosage.forms.,.
human.urine.
(dil. and.spiked)
(a).[678]
(b).[1418]
Glibenclamide
Antidiabetic.agent.(SO
2
-urea.
hydrazide)
C/PO.(unm.),.C/PO.
(+
Sephadex
)
CV,.DPV
Studies.on.adsor..accum..mechanism
o.c.,.s.e.:.0.04.M.BRB.(pH.2);.1.×.10
−9
-5.×.
10
−7
.M,.LOD:.0.4.nM.(
t
AC
.=.180.s)
pharm..forms..
(tablets).human.
urine
[2571]
Gliclazide
Antidiabetic.agent.(SO
2
-urea.
hydrazide)
C/PO.(unm.)
DPV,.CP,.CM
Study.on.electrode.oxidn..(two.peaks),.
pH 2-12;.lin.range:.1.×.10
−8
-5.×.10
−6
.M
pharm..forms..
(dosage.tablets)
[2572]
Heroin
Narcoticum,.abuse.
drug (alkaloid.sp..from.
Morphin
.gr.)
(a).C/PO.(unm.)
(b).C/PO.(+Ru(bpy)
3
-
ZeY
)
(c).CILE.[ctng..(MIM).
PF
6
.+.Ru
III
-complex.
as reagt.]
(a).CV,.LSV
(b).FIA-ECL
(c).ECL
(a).Study.on.oxidn..mechanism.and.
pH-effect;.lin..range:.1.×.10
−7−
1.×.10
−5
.M
(b).mdf.:.altered.zeolite.Y,.LOD:.1.μM
(c).lin.:.2.×.10
−9−
2.×.10
−5
.M,.RSD.<.5%
(a).Seized.drug.s.
(b).Model.solns.
(c).Human.serum.
(
R
R
.=.94%-101%)
(a).[2573]
(c).[502]
(c).[502]
Honokiol
Antibacterial.agent.(nat..
biphenol.ctnd..in.
Magnolia
.
lower)
C/PO.(+mpSiO
2
.and.surf.)
CV,.2
nd
DeLV
Enhanced.oxidn..peak.(
E
.=.+0.3.vs..ref.).
by cationic.surfactant;.pH.6.5,.LOD:.
0.5.μg.L
−1
;.simult..detn..with.
Magnolol
pharm..preps,.
(Chinese.med.)
[1671]
Hydrocortisone
Antiinlammatory.ag..(nat..
cortico-steroid)
C/PO.(unm.).C/PO.
(+β-cyclodextrin)
CV,.DPV
Study.on.the.inclusion.effect.of.modif.;.
lin.r.:.4.×.10
−7
-3.×.10
−5
.M;.simult..detn..
with.
Dexamethasone
.and.
Prednisone
pharm..forms,.biol..
luids
[2550]
Hydrochloro-
thiazide
Antihypertension.and.
irst-line.diuretic.agent.
(subst..sulfonamide)
C/PO.(+Fc-DCA)
CV,.CA,.SWV
Study.on.el.-catalytic.effect.of.modif..on.
oxidn.;.DCA:.dicarboxylic.acid.;.pH.9;.
lin.r.:.8.0.×.10
−8
-5.8.×.10
−6
.M
comm..drug,.human.
urine
[1537]
Part 2
: Substances “
I-Z”
Imipramine
Antidepressant.(tricyclic.der.)
(a).C/PO.(PV-N-
imidazole)
(b).C/PO.(fatty.acid)
(a).CV,.DPV
(b).DPASV
(a).pH-,.opt..and.interfs..studies
(b).pH.9,.0.1-8.μM;.opt..+.interfs.
(a,b).Dosage.forms
(b).Biological.luids
(a).[2508]
(b).[1675]
(
continued
)
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