Brain Ischemic Injury in Rodents: The Protective Effect of EPO - Tissue-Protective Cytokines: Methods and Protocols - page 96

12. Lapchak PA, Araujo DM (2007) Advances in
ischemic stroke treatment: neuroprotective
and combination therapies. Expert Opin
Emerg Drugs 12:97-112
13. Khaja AM (2008) Acute ischemic stroke man-
agement: administration of thrombolytics, neu-
roprotectants, and general principles of medical
management. Neurol Clin 26:943-961, viii
14. Auriel E, Bornstein NM (2010) Neuroprotection
in acute ischemic stroke-current status. J Cell
Mol Med 14:2200-2202
15. O'Collins VE et al (2006) 1,026 Experimental
treatments in acute stroke. Ann Neurol
59:467-477
16. Pandya RS et al (2011) Central nervous system
agents for ischemic stroke: neuroprotection
mechanisms. Cent Nerv Syst Agents Med Chem.
Available at: http://www.ncbi.nlm.nih.gov/
pubmed/21521165 . Accessed 28 Apr 2011.
17. Rosenberg N, Chen M, Prabhakaran S (2010)
New devices for treating acute ischemic stroke.
Recent Pat CNS Drug Discov 5:118-134
18. Fisher M et al (2009) Update of the stroke
therapy academic industry roundtable preclini-
cal recommendations. Stroke 40:2244-2250
19. Dirnagl U (2006) Bench to bedside: the quest
for quality in experimental stroke research.
J Cereb Blood Flow Metab 26:1465-1478
20. Macleod MR et al (2009) Good laboratory
practice: preventing introduction of bias at the
bench. Stroke 40:e50-e52
21. Peters JL et al (2006) A systematic review of
systematic reviews and meta-analyses of animal
experiments with guidelines for reporting.
J Environ Sci Health B 41:1245-1258
22. Crossley NA et al (2008) Empirical evidence
of bias in the design of experimental stroke
studies: a metaepidemiologic approach. Stroke
39:929-934
23. DeGraba TJ, Pettigrew LC (2000) Why do
neuroprotective drugs work in animals but not
humans? Neurol Clin 18:475-493
24. Shuaib A (2006) Neuroprotection in acute
ischemic stroke: are we there yet? Int J Stroke
1:100-101
25. Fisher M, Tatlisumak T (2005) Use of animal
models has not contributed to development of
acute

29. Kong LQ et al (2004) Improvements in the
intraluminal thread technique to induce focal
cerebral ischaemia in rabbits. J Neurosci
Methods 137:315-319
30. Barber PA et al (2005) Early T1- and
T2-weighted MRI signatures of transient and
permanent middle cerebral artery occlusion in
a murine stroke model studied at 9.4 T.
Neurosci Lett 388:54-59
31. Chiang T, Messing RO, Chou W-H (2011)
Mouse model of middle cerebral artery occlu-
sion. J Vis Exp. Available at: http://www.ncbi.
nlm.nih.gov/pubmed/21372780 . Accessed 8
Nov 2011.
32. Duverger D, MacKenzie ET (1988) The
quantification of cerebral infarction following
focal ischemia in the rat: influence of strain, arte-
rial pressure, blood glucose concentration, and
age. J Cereb Blood Flow Metab 8:449-461
33. Shapira S et al (2002) Aging has a complex
effect on a rat model of ischemic stroke. Brain
Res 925:148-158
34. Oliff HS et al (1995) The role of strain/vendor
differences on the outcome of focal ischemia
induced by intraluminal middle cerebral artery
occlusion in the rat. Brain Res 675:20-26
35. Cai H et al (1998) Photothrombotic middle
cerebral artery occlusion in spontaneously
hypertensive rats: influence of substrain, gen-
der, and distal middle cerebral artery patterns
on infarct size. Stroke 29:1982-1986, discus-
sion 1986-1987
36. Coyle P (1986) Different susceptibilities to
cerebral infarction in spontaneously hyperten-
sive (SHR) and normotensive Sprague-Dawley
rats. Stroke 17:520-525
37. Takaba H, Fukuda K, Yao H (2004) Substrain
differences, gender, and age of spontaneously
hypertensive rats critically determine infarct
size produced by distal middle cerebral artery
occlusion. Cell Mol Neurobiol 24:589-598
38. Mies G et al (1999) Hemodynamics and metab-
olism in stroke-prone spontaneously hyperten-
sive rats before manifestation of brain infarcts.
J Cereb Blood Flow Metab 19:1238-1246
39. Bardutzky J et al (2005) Differences in isch-
emic lesion evolution in different rat strains
using diffusion and perfusion imaging. Stroke
36:2000-2005
40. Letourneur A et al (2011) Impact of genetic
and renovascular chronic arterial hypertension
on the acute spatiotemporal evolution of the
ischemic penumbra: a sequential study with
MRI in the rat. J Cereb Blood Flow Metab
31:504-513
41. Rewell SSJ et al (2010) Inducing stroke in
aged, hypertensive, diabetic rats. J Cereb
Blood Flow Metab 30:729-733
42. Brait VH et al (2010) Mechanisms contribut-
ing to cerebral infarct size after stroke: gender,

stroke therapies: con. Stroke

36:2324-2325
26. Tamura A et al (1981) Focal cerebral ischae-
mia in the rat: 1 Description of technique and
early neuropathological consequences follow-
ing middle cerebral artery occlusion. J Cereb
Blood Flow Metab 1:53-60
27. Longa EZ et al (1989) Reversible middle cere-
bral artery occlusion without craniectomy in
rats. Stroke 20:84-91
28. Kawamura S et al (1991) Rat middle cerebral
artery occlusion using an intraluminal thread
technique. Acta Neurochir (Wien) 109:126-132