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Fig. 12.6.
Radiolysis of Z-DNA. Frequency of frank SSBs (
top
) and damaged bases (ALSs,
bottom
).
Solid lines
were calculated using RADACK procedure according to Spotheim-Maurizot et al. (2003,
with permission)
fact that the size of the minor grove in B-DNA varies substantially with the base
sequence and influences markedly the accessibility to H4
′
and H5
′
2 but barely
that to H5
′
1. When the width of the minor groove is <4.5 Å, the accessibility of
H4
′
and H5
′
2 drastically diminishes and so does the frequency of induced frank
SSBs.
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