DNA and Double-Stranded Oligonucleotides - Free-Radical-Induced DNA Damage and Its Repair - page 355

Fig. 12.5. Radiolysis of B-DNA. Frequency of frank SSBs ( top ) and damaged bases (ALSs, bottom ).
Solid lines were calculated using RADACK procedure according to Spotheim-Maurizot et al. (2003,
with permission)

nucleotide site and the accessibility to H4 2 atoms of each nucleotide.

Both patterns exhibit also this strong sequence dependence. Moreover, the width
of the minor groove measured on the molecular model of the DNA of the same
sequence presents the same sequence dependence (Fig. 12.3). This is due to the

′ and H5 ′