Nanoparticles to Cross Biological Barriers - Biomaterials Science: An Integrated Clinical and Engineering Approach - page 118

159. D.P. McIntosh, X. Tan, P. Oh, J.E. Schnitzer, Targeting endothelium and its
dynamic caveolae for tissue-specific transcytosis in vivo: A pathway to over-
come cell barriers to drug and gene delivery, Proceedings of the National Academy
of Sciences of the United States of America 99 (2002) 1996-2001.
160. J.E. Schnitzer, Caveolae: From basic trafficking mechanisms to targeting trans-
cytosis for tissue-specific drug and gene delivery in vivo, Adv. Drug Deliv. Rev.
49 (2001) 265-280.
161. R.K. Jain, T. Stylianopoulos, Delivering nanomedicine to solid tumors, Nat Rev
Clin Oncol 7 (2010) 653-664.
162. R. Cairns, I. Papandreou, N. Denko, Overcoming physiologic barriers to can-
cer treatment by molecularly targeting the tumor microenvironment, Molecular
Cancer Research 4 (2006) 61-70.
163. R.K. Jain, Transport of molecules in the tumor interstitium: A review, Cancer
Research 47 (1987) 3039-3051.
164. T.T. Goodman, C.P. Ng, S.H. Pun, 3-D tissue culture systems for the evaluation
and optimization of nanoparticle-based drug carriers, Bioconjug. Chem. 19 (2008)
1951-1959.
165. S. Ramanujan, A. Pluen, T.D. McKee, E.B. Brown, Y. Boucher, R.K. Jain, Diffusion
and convection in collagen gels: Implications for transport in the tumor intersti-
tium, Biophys. J. 83 (2002) 1650-1660.
166. P. Calvo, B. Gouritin, H. Chacun, D. Desmaële, J. D'Angelo, J. Noel, D. Georgin,
E. Fattal, J.P. Andreux, P. Couvreur, Long-circulating PEGylated polycyanoacry-
late nanoparticles as new drug carrier for brain delivery, Pharm. Res. 18 (2001)
1157-1166.
167. V. Rousseau, B. Denizot, D. Pouliquen, P. Jallet, J. Le Jeune, Investigation of
blood-brain barrier permeability to magnetite-dextran nanoparticles (MD3)
after osmotic disruption in rats, Magnetic Resonance Materials in Physics, Biology
and Medicine 5 (1997) 213-222.
168. R.K. Jain, Transport of molecules, particles, and cells in solid tumors, Annu. Rev.
Biomed. Eng . 1 (1999) 241-263.
169. A. Pluen, Y. Boucher, S. Ramanujan, T.D. McKee, T. Gohongi, E. di Tomaso,
E.B. Brown, Y. Izumi, R.B. Campbell, D.A. Berk, R.K. Jain, Role of tumor-host
interactions in interstitial diffusion of macromolecules: Cranial vs. subcutane-
ous tumors, Proceedings of the National Academy of Sciences of the United States of
America 98 (2001) 4628-4633.
170. S.K. Hobbs, W.L. Monsky, F. Yuan, W.G. Roberts, L. Griffith, V.P. Torchilin, R.K.
Jain, Regulation of transport pathways in tumor vessels: Role of tumor type and
microenvironment, Proceedings of the National Academy of Sciences of the United
States of America 95 (1998) 4607-4612.
171. A. Krol, J. Maresca, M.W. Dewhirst, F. Yuan, Available volume fraction of mac-
romolecules in the extravascular space of a fibrosarcoma: Implications for drug
delivery, Cancer Research 59 (1999) 4136-4141.
172. G.M. Thurber, M.M. Schmidt, K.D. Wittrup, Antibody tumor penetration:
Transport opposed by systemic and antigen-mediated clearance, Adv. Drug
Deliv. Rev. 60 (2008) 1421-1434.
173. G.M. Thurber, K.D. Wittrup, Quantitative spatiotemporal analysis of antibody
fragment diffusion and endocytic consumption in tumor spheroids, Cancer
Research 68 (2008) 3334-3341.