Chemistry Reference
In-Depth Information
Table 7.2 Ru-Co bimetallic system for the aerobic oxidation of alcohols.
RuCl
3
nH
2
O(1mol%)
Co(OAc)
2
4H
2
O(1mol%)
OH
O
R
1
R
2
R
1
R
2
CH
3
CHO (4 equiv)
EtOAc, RT, O
2
(1 atm)
Entry
Substrate
Product
Yield
a
(%)
1
96
OH
CO
2
H
OH
O
2
89
OH
O
3
95
OH
O
4
94
Ph
Ph
OH
O
5
78
Ph
CO
2
Me
Ph
CO
2
Me
a
Isolated yield.
Co
III
CH
3
CO
+
H
+
CH
3
CO
3
+
H
+
O
2
CH
3
CHO
MeCO
3
H
MeCO
2
H
Co
II
CH
3
CHO
Ru
III
Ru
V
=O
O
OH
R
1
R
2
R
1
R
2
+
H
2
O
Scheme 7.9 Proposed mechanism of the catalytic aerobic oxidation of alcohols with
the Ru-Co bimetallic system.
but the authors suggested that osmium is probably responsible for the
oxidation step whereas copper could act as an electron-transfer agent
between molecular oxygen and the reduced osmium complex.
19a
Search WWH ::
Custom Search